The evidence matrix

103 graded links between 57 conditions and 69 interventions. Each cell is a direction and an evidence grade, read from the intervention’s own entry.

Improves
May improve
No clear effect
May worsen
Worsens
· the letter is the evidence grade, A strongest

As lists · As a grid

30 conditions × 24 interventions · 40 of 103 links · 27 more conditions and 45 more interventions not drawn — draw them all

Conditions in rows, interventions in columns. Each cell gives the direction of the effect and its evidence grade; an empty cell means the library grades no link.
Condition	Ashwagandha	Caffeine + L-Theanine	Cold exposure	Creatine	Magnesium L-Threonate	Omega-3 (EPA/DHA)	Protein intake	Sleep architecture	Zone 2 training	Magnesium	Vitamin D	Inositol (Myo-Inositol)	Melatonin	Vitamin B12	Alpha-Lipoic Acid	Andrographis	Apple Cider Vinegar	Artichoke Leaf Extract	Banaba (Corosolic Acid)	Berberine	Bergamot (Citrus Bergamia)	Beta-Glucans	Bitter Melon	Black Cohosh
Hypertension11 linked
Migraine6 linked
Depression5 linked
Osteoarthritis5 linked
Anxiety4 linked
Type 2 diabetes4 linked
Type 2 diabetes / prediabetes4 linked
Benign prostatic hyperplasia3 linked
Dyslipidemia3 linked
Insomnia3 linked
Menopause symptoms3 linked
Chronic venous insufficiency2 linked
Depression (mild-moderate)2 linked
IBS2 linked
PMS2 linked
Recurrent urinary-tract infection2 linked
Sarcopenia (age-related muscle loss)2 linked
ADHD (adult)1 linked
Advanced kidney disease1 linked
Age-related cognitive decline1 linked
Age-related macular degeneration1 linked
Anxiety disorders1 linked
Atrial fibrillation1 linked
Autoimmune disease1 linked
Burnout / chronic fatigue1 linked
Cardiovascular disease1 linked
Chronic heart failure1 linked
Chronic kidney disease1 linked
Cognitive decline1 linked
Common cold1 linked

Rows and columns are ordered by how many links each carries; the grid draws the first 30 conditions and 24 interventions unless asked for all.

Directions and grades are read from each intervention’s own entry in this library. They describe the evidence for a link, not what anyone should take, and they are no substitute for a clinician who knows the person.