What Creatine is graded against
4 conditions the Creatine entry grades it against, grouped by direction.
Improves1 link
- Sarcopenia (age-related muscle loss)Evidence grade B
With resistance training in older adults — the ISSN-endorsed clinical use case
May improve2 links
- DepressionEvidence grade C
Adjunct RCTs show faster SSRI response; small samples so far
- Type 2 diabetesEvidence grade C
Modestly better glycemic control when paired with training
No clear effect1 link
- Chronic kidney diseaseEvidence grade B
Raises the creatinine lab without harming function — flag supplementation to your nephrologist
Directions and grades are read from each intervention’s own entry in this library. They describe the evidence for a link, not what anyone should take, and they are no substitute for a clinician who knows the person.