The evidence matrix

103 graded links between 57 conditions and 69 interventions. Each cell is a direction and an evidence grade, read from the intervention’s own entry.

Improves
May improve
No clear effect
May worsen
Worsens
· the letter is the evidence grade, A strongest

As lists · As a grid

57 conditions × 69 interventions · 103 of 103 links

Conditions in rows, interventions in columns. Each cell gives the direction of the effect and its evidence grade; an empty cell means the library grades no link.
Condition	Ashwagandha	Caffeine + L-Theanine	Cold exposure	Creatine	Magnesium L-Threonate	Omega-3 (EPA/DHA)	Protein intake	Sleep architecture	Zone 2 training	Magnesium	Vitamin D	Inositol (Myo-Inositol)	Melatonin	Vitamin B12	Alpha-Lipoic Acid	Andrographis	Apple Cider Vinegar	Artichoke Leaf Extract	Banaba (Corosolic Acid)	Berberine	Bergamot (Citrus Bergamia)	Beta-Glucans	Bitter Melon	Black Cohosh	Boswellia	Butterbur	Choline	Cocoa Flavanols	Coenzyme Q10	Collagen Peptides	Cranberry	Curcumin (Turmeric)	D-Mannose	DGL (Licorice)	Diosmin / Hesperidin	Evening Primrose Oil (GLA)	Feverfew	Garlic	Ginger	Glucosamine	Grape Seed Extract	Gymnema Sylvestre	Hibiscus	Horse Chestnut	Huperzine A	Hyaluronic Acid (Oral)	Kava	L-Arginine	L-Lysine	Lutein & Zeaxanthin	Mucuna Pruriens (L-Dopa)	Nattokinase	Olive Leaf Extract	Passionflower	Peppermint Oil	Potassium	Probiotics	Psyllium Husk	Pygeum	Red Clover	Rhodiola Rosea	Riboflavin (B2)	Saffron	Saw Palmetto	Soy Isoflavones	St. John's Wort	Stinging Nettle	Vitex (Chasteberry)	Zinc-Carnosine
Hypertension11 linked
Migraine6 linked
Depression5 linked
Osteoarthritis5 linked
Anxiety4 linked
Type 2 diabetes4 linked
Type 2 diabetes / prediabetes4 linked
Benign prostatic hyperplasia3 linked
Dyslipidemia3 linked
Insomnia3 linked
Menopause symptoms3 linked
Chronic venous insufficiency2 linked
Depression (mild-moderate)2 linked
IBS2 linked
PMS2 linked
Recurrent urinary-tract infection2 linked
Sarcopenia (age-related muscle loss)2 linked
ADHD (adult)1 linked
Advanced kidney disease1 linked
Age-related cognitive decline1 linked
Age-related macular degeneration1 linked
Anxiety disorders1 linked
Atrial fibrillation1 linked
Autoimmune disease1 linked
Burnout / chronic fatigue1 linked
Cardiovascular disease1 linked
Chronic heart failure1 linked
Chronic kidney disease1 linked
Cognitive decline1 linked
Common cold1 linked
Delayed sleep phase1 linked
Dementia1 linked
Diabetic neuropathy1 linked
Erectile dysfunction1 linked
Functional dyspepsia1 linked
Gastritis / gut-barrier1 linked
Generalized anxiety1 linked
Hypertriglyceridemia1 linked
IBS / constipation1 linked
Jet lag1 linked
Knee osteoarthritis1 linked
Liver conditions1 linked
Metabolic syndrome1 linked
Nausea1 linked
Obesity / weight management1 linked
Osteoporosis1 linked
Osteoporosis / bone loss1 linked
Parkinson's disease1 linked
PCOS1 linked
Pernicious / macrocytic anemia1 linked
Pregnancy (fetal development)1 linked
Raynaud's syndrome1 linked
Recurrent cold sores1 linked
Rheumatoid arthritis1 linked
Seasonal low mood1 linked
Stress-driven insomnia1 linked
Subclinical hypothyroidism1 linked

Rows and columns are ordered by how many links each carries; the grid draws the first 30 conditions and 24 interventions unless asked for all.

Directions and grades are read from each intervention’s own entry in this library. They describe the evidence for a link, not what anyone should take, and they are no substitute for a clinician who knows the person.