Safety · Supplement
Choline: side effects, safety & interactions
High doses cause fishy odor and GI effects; very high intakes may raise TMAO.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
High doses cause fishy odor and GI effects; very high intakes may raise TMAO.
Interactions to respect
No major interactions are on record for Choline at typical doses, but tell your clinician about everything you take.
What Choline is
Choline is an essential nutrient (vitamin-like) for cell membranes, the neurotransmitter acetylcholine, and methylation. Most diets fall short of the adequate intake.
The honest bottom line
An overlooked essential — prioritize adequacy, especially in pregnancy. Eggs are the easiest source; most prenatals skimp on it.
Related reading
Entries that share this one's tags or conditions.
- CholineAn essential nutrient most people under-eat — critical in pregnancy for fetal brain development.Evidence grade B
- Choline for Cognition (replete adults)Evidence grade C — WeakEvidence grade C
- Choline for Fetal brain development (pregnancy)Evidence grade B — Adequacy mattersEvidence grade B
- Choline for Liver fatEvidence grade C — Deficiency raises riskEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.