Supplements for inflammation

9 compounds relevant to inflammation, ranked by overall evidence grade.

Overall grade: Grade B
Last revised: Jul 10, 2026; 9
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

3 at grade B · 5 at grade C · 1 at grade D — 9 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Curcumin (Turmeric)A genuine anti-inflammatory for joints and mood — if you solve its terrible absorption; ignore the cancer-cure hype.	Evidence grade B	Unclear	mixed
BoswelliaAn anti-inflammatory resin with some of the better osteoarthritis-pain data among botanicals.	Evidence grade B	Unclear	mixed
GingerOne of the best-evidenced natural anti-nausea agents, with modest anti-inflammatory and pain data on top.	Evidence grade B	Unclear	mixed
FeverfewA migraine-prevention herb with modest, inconsistent trial support.	Evidence grade C	Unclear	mixed
BromelainA pineapple enzyme with modest evidence for post-surgical swelling and sinusitis.	Evidence grade C	Unclear	mixed
Cat's ClawAn Amazonian anti-inflammatory bark with early joint-pain evidence and immune-modulating caveats.	Evidence grade C	Unclear	mixed
Cissus QuadrangularisAn Ayurvedic bone-and-joint herb with early evidence for fracture healing and joint pain.	Evidence grade C	Unclear	mixed
Black Seed Oil (Nigella sativa)A traditional 'cure-all' seed oil (thymoquinone) with real, modest signals for blood pressure, glucose and lipids.	Evidence grade C	Unclear	mixed
SerrapeptaseA proteolytic enzyme sold for inflammation and pain with weak, low-quality human evidence.	Evidence grade D	Unclear	mixed

Curcumin (Turmeric)Evidence grade B
A genuine anti-inflammatory for joints and mood — if you solve its terrible absorption; ignore the cancer-cure hype.
Unclearmixed
BoswelliaEvidence grade B
An anti-inflammatory resin with some of the better osteoarthritis-pain data among botanicals.
Unclearmixed
GingerEvidence grade B
One of the best-evidenced natural anti-nausea agents, with modest anti-inflammatory and pain data on top.
Unclearmixed
FeverfewEvidence grade C
A migraine-prevention herb with modest, inconsistent trial support.
Unclearmixed
BromelainEvidence grade C
A pineapple enzyme with modest evidence for post-surgical swelling and sinusitis.
Unclearmixed
Cat's ClawEvidence grade C
An Amazonian anti-inflammatory bark with early joint-pain evidence and immune-modulating caveats.
Unclearmixed
Cissus QuadrangularisEvidence grade C
An Ayurvedic bone-and-joint herb with early evidence for fracture healing and joint pain.
Unclearmixed
Black Seed Oil (Nigella sativa)Evidence grade C
A traditional 'cure-all' seed oil (thymoquinone) with real, modest signals for blood pressure, glucose and lipids.
Unclearmixed
SerrapeptaseEvidence grade D
A proteolytic enzyme sold for inflammation and pain with weak, low-quality human evidence.
Unclearmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Feverfew (grade C); Bromelain (grade C); Cat's Claw (grade C); Cissus Quadrangularis (grade C); Black Seed Oil (Nigella sativa) (grade C); Serrapeptase (grade D).
Studies disagree: Curcumin (Turmeric) (mixed agreement); Boswellia (mixed agreement); Ginger (mixed agreement).

The evidence in words

The shortlist

Every compound in the knowledge base tagged to inflammation, ordered by how strong its overall evidence is. Start at the top; the grade is the honest filter.

Worth considering first

Curcumin (Turmeric) (B) — A genuine anti-inflammatory for joints and mood — if you solve its terrible absorption; ignore the cancer-cure hype. · Boswellia (B) — An anti-inflammatory resin with some of the better osteoarthritis-pain data among botanicals. · Ginger (B) — One of the best-evidenced natural anti-nausea agents, with modest anti-inflammatory and pain data on top.

Lower-evidence options

Feverfew (C) — A migraine-prevention herb with modest, inconsistent trial support. · Bromelain (C) — A pineapple enzyme with modest evidence for post-surgical swelling and sinusitis. · Cat's Claw (C) — An Amazonian anti-inflammatory bark with early joint-pain evidence and immune-modulating caveats. · Cissus Quadrangularis (C) — An Ayurvedic bone-and-joint herb with early evidence for fracture healing and joint pain. · Black Seed Oil (Nigella sativa) (C) — A traditional 'cure-all' seed oil (thymoquinone) with real, modest signals for blood pressure, glucose and lipids. · Serrapeptase (D) — A proteolytic enzyme sold for inflammation and pain with weak, low-quality human evidence.

Goes with

Curcumin (Turmeric)Grade BEvidence grade B
BoswelliaGrade BEvidence grade B
GingerGrade BEvidence grade B
FeverfewGrade CEvidence grade C
BromelainGrade CEvidence grade C
Cat's ClawGrade CEvidence grade C
Cissus QuadrangularisGrade CEvidence grade C
Black Seed Oil (Nigella sativa)Grade CEvidence grade C

Entries that share this one's tags or conditions.

NSAIDsNon-steroidal anti-inflammatory drugs for pain, fever, and inflammation.Evidence grade A
Black Seed Oil (Nigella sativa) for Blood pressureEvidence grade C — ModestEvidence grade C
Black Seed Oil (Nigella sativa) for Glucose / HbA1cEvidence grade C — ModestEvidence grade C
Black Seed Oil (Nigella sativa) for LDL cholesterolEvidence grade C — ModestEvidence grade C

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.