Compound or practice · Supplement
Cat's Claw
An Amazonian anti-inflammatory bark with early joint-pain evidence and immune-modulating caveats.
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Joint pain (OA/RA)Evidence grade C
Small trials
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Joint pain (OA/RA) (grade C).
- Caution with Immunosuppressants: Immune modulation may oppose the drug.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
ImmunosuppressantsCaution
Immune modulation may oppose the drug.
The evidence in words
What it is
Cat's claw (Uncaria tomentosa) is a South American vine used for inflammation and joint pain.
How it works
Alkaloids and other compounds have anti-inflammatory and immune-modulating activity.
What the evidence shows
Small trials suggest reduced osteoarthritis and rheumatoid-arthritis joint pain; evidence is limited. Its immune modulation warrants caution with immunosuppressants and autoimmune disease.
Safety & interactions
Generally tolerated; caution with immunosuppressants and autoimmune conditions. immunosuppressants — Immune modulation may oppose the drug.
Bottom line
An early-evidence joint anti-inflammatory. Reasonable to trial for OA; mind the immune interactions.
Related reading
Entries that share this one's tags or conditions.
- Cat's Claw for Joint pain (OA/RA)Evidence grade C — Small trialsEvidence grade C
- Cat's Claw: side effects, safety & interactionsGenerally tolerated; caution with immunosuppressants and autoimmune conditions.Evidence grade C
- Curcumin (Turmeric)A genuine anti-inflammatory for joints and mood — if you solve its terrible absorption; ignore the cancer-cure hype.Evidence grade B
- AHCCA cultured-mushroom immune extract with a genuinely interesting HPV-clearance signal.Evidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.