Compound or practice · Supplement

Boswellia

An anti-inflammatory resin with some of the better osteoarthritis-pain data among botanicals.

Overall grade
Grade B
Last revised
1
graded outcome
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

2 at grade B — 2 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Osteoarthritis pain/functionEvidence grade B

    Standardized extracts

    Moderatemixed

Conditions

How the entry reads its effect on diagnosed conditions: the direction first, then the grade. Never a substitute for the person who treats you.

  • Osteoarthritis ImprovesReasonable RCT supportGrade B

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Studies disagree: Osteoarthritis pain/function (mixed agreement).

Interactions

Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.

The evidence in words

What it is

Boswellia serrata resin (standardized to boswellic acids, notably AKBA) is used for inflammatory joint pain.

How it works

Boswellic acids inhibit 5-lipoxygenase and leukotriene synthesis, a distinct anti-inflammatory pathway from NSAIDs.

What the evidence shows

Multiple small RCTs show reduced osteoarthritis pain and improved function, sometimes within a week, with reasonable consistency for a botanical. Standardized high-AKBA extracts perform best. A credible option for joint inflammation.

How to use it

100–250 mg/day of a high-AKBA standardized extract (product-dependent).

Safety & interactions

Well tolerated; occasional GI upset. Curcumin (Turmeric) — Complementary anti-inflammatory pathways for joints.

Bottom line

One of the more convincing joint botanicals for osteoarthritis pain. Use a standardized high-AKBA extract and give it a couple of weeks.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
100–250 mg/day high-AKBA extract.

Goes with

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.