Medication · Medication
NSAIDs
Non-steroidal anti-inflammatory drugs for pain, fever, and inflammation.
- Last revised
- 0
- graded outcomes
- 0
- references listed
A medication reference built from the interaction graph. It is not prescribing information — the label and your prescriber are.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Caution with SSRIs / SNRIs: SSRIs plus NSAIDs sharply raise GI-bleeding risk — a well-documented pairing.
- Caution with Anticoagulants: Additive bleeding risk plus displacement — a dangerous, common combination.
- Caution with BP meds: NSAIDs blunt blood-pressure control and stress the kidneys, especially with ACE inhibitors/diuretics.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
SSRIs / SNRIsCaution
SSRIs plus NSAIDs sharply raise GI-bleeding risk — a well-documented pairing.
AnticoagulantsCaution
Additive bleeding risk plus displacement — a dangerous, common combination.
BP medsCaution
NSAIDs blunt blood-pressure control and stress the kidneys, especially with ACE inhibitors/diuretics.
The evidence in words
What it is
Non-steroidal anti-inflammatory drugs for pain, fever, and inflammation.
How it works
They inhibit COX enzymes, reducing prostaglandins — which also thins the protective stomach lining and affects kidney blood flow.
What it's used for
Pain, fever, inflammatory conditions.
Supplement & drug interactions
NSAIDs has 3 documented interactions mapped below and in the interactions graph. The bleeding theme dominates: NSAIDs plus SSRIs or plus anticoagulants sharply raise GI-bleeding risk, and they blunt blood-pressure control (worse with ACE inhibitors/diuretics). Gut-protective supplements (zinc-carnosine) are studied against NSAID damage.
The rule
This is a medication reference for spotting interactions, not dosing advice. Every change to a supplement stack around a prescription belongs with the person who prescribes it.
Related reading
Entries that share this one's tags or conditions.
- Anticoagulants (Warfarin)Warfarin is a vitamin-K-antagonist anticoagulant with a narrow therapeutic window measured by INR.Evidence grade A
- AntiplateletsDrugs that reduce platelet clumping to prevent arterial clots.Evidence grade A
- CorticosteroidsPotent anti-inflammatory and immunosuppressant steroids.Evidence grade A
- DOACsDirect oral anticoagulants — newer blood thinners that, unlike warfarin, need no routine INR monitoring.Evidence grade A
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.