Blood-Pressure Medications

The families of drugs that lower blood pressure — ACE inhibitors, ARBs, calcium-channel blockers, beta-blockers.

Last revised: Jul 10, 2026; 0
graded outcomes: 0
references listed

A medication reference built from the interaction graph. It is not prescribing information — the label and your prescriber are.

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Caution with Magnesium: Mild additive blood-pressure lowering.
Caution with Potassium: With ACE inhibitors/ARBs/K-sparing diuretics, risk of dangerous hyperkalemia.
Caution with L-Citrulline: Additive blood-pressure lowering — cuff it if on BP meds.
Caution with Garlic: Additive blood-pressure lowering.
Caution with Beetroot / Dietary Nitrate: Additive blood-pressure lowering.
Caution with Quercetin: Additive blood-pressure lowering.
Caution with Hawthorn: Additive blood-pressure/cardiac effects.
Caution with L-Arginine: Additive blood-pressure lowering.
Caution with Olive Leaf Extract: Additive blood-pressure lowering.
Caution with Cocoa Flavanols: Additive blood-pressure lowering.
Caution with Pycnogenol (Pine Bark): Additive blood-pressure lowering.
Caution with Hibiscus: Additive blood-pressure lowering.
Caution with Black Seed Oil (Nigella sativa): Additive blood-pressure lowering.
Caution with Grapefruit: Grapefruit raises several calcium-channel-blocker levels, exaggerating blood-pressure drops.
Caution with NSAIDs: NSAIDs blunt blood-pressure control and stress the kidneys, especially with ACE inhibitors/diuretics.

Interactions

Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.

MagnesiumCaution
Mild additive blood-pressure lowering.
PotassiumCaution
With ACE inhibitors/ARBs/K-sparing diuretics, risk of dangerous hyperkalemia.
L-CitrullineCaution
Additive blood-pressure lowering — cuff it if on BP meds.
GarlicCaution
Additive blood-pressure lowering.
Beetroot / Dietary NitrateCaution
Additive blood-pressure lowering.
QuercetinCaution
Additive blood-pressure lowering.
HawthornCaution
Additive blood-pressure/cardiac effects.
L-ArginineCaution
Additive blood-pressure lowering.
Olive Leaf ExtractCaution
Additive blood-pressure lowering.
Cocoa FlavanolsCaution
Additive blood-pressure lowering.
Pycnogenol (Pine Bark)Caution
Additive blood-pressure lowering.
HibiscusCaution
Additive blood-pressure lowering.
Black Seed Oil (Nigella sativa)Caution
Additive blood-pressure lowering.
GrapefruitCaution
Grapefruit raises several calcium-channel-blocker levels, exaggerating blood-pressure drops.
NSAIDsCaution
NSAIDs blunt blood-pressure control and stress the kidneys, especially with ACE inhibitors/diuretics.

The evidence in words

What it is

The families of drugs that lower blood pressure — ACE inhibitors, ARBs, calcium-channel blockers, beta-blockers.

How it works

Each lowers pressure by a different route; supplements that also lower pressure add to the effect, and some raise drug levels.

What it's used for

Hypertension, heart failure, post-heart-attack.

Supplement & drug interactions

Blood-Pressure Medications has 15 documented interactions mapped below and in the interactions graph. Blood-pressure-lowering supplements (magnesium, potassium, garlic, beetroot/nitrate, citrulline, CoQ10) are additive — usually fine, worth a cuff check. Two sharp cautions: potassium plus ACE inhibitors/ARBs risks hyperkalemia, and grapefruit raises some calcium-channel-blocker levels. NSAIDs blunt control.

The rule

This is a medication reference for spotting interactions, not dosing advice. Every change to a supplement stack around a prescription belongs with the person who prescribes it.

Entries that share this one's tags or conditions.

Cocoa Flavanols for Blood pressureEvidence grade B — Modest reductionEvidence grade B
Hibiscus for Blood pressureEvidence grade B — Several mmHgEvidence grade B
Nattokinase for Blood pressureEvidence grade C — ModestEvidence grade C
ADHD StimulantsPrescription stimulants for attention-deficit/hyperactivity disorder.Evidence grade A

Sources

This entry lists no references of its own.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.