Compound or practice · Supplement

Hawthorn

A traditional cardiac tonic with some heart-failure-symptom data — but modern therapy has moved past it.

Overall grade
Grade C
Last revised
1
graded outcome
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

1 at grade C — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Heart-failure symptoms (adjunct)Evidence grade C

    Hard outcomes neutral

    Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Heart-failure symptoms (adjunct) (grade C).
  • Caution with Blood-pressure medications: Additive blood-pressure/cardiac effects.

Interactions

Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.

  • Blood-pressure medicationsCaution

    Additive blood-pressure/cardiac effects.

The evidence in words

What it is

Hawthorn (Crataegus) extract is a flavonoid-rich botanical used for heart health.

How it works

Mild positive inotropic and vasodilatory effects and antioxidant activity.

What the evidence shows

Older trials showed symptom improvement in mild heart failure as an adjunct, but a large trial (SPICE) was neutral on hard outcomes, and it is not part of modern guideline therapy. Interacts with cardiac drugs.

How to use it

Standardized extract if used, and only alongside — not instead of — medical heart-failure care.

Safety & interactions

Generally tolerated; can potentiate cardiac and blood-pressure medications. antihypertensives — Additive blood-pressure/cardiac effects.

Bottom line

A gentle cardiac tonic that modern therapy has outgrown. Never a substitute for real heart-failure treatment; coordinate with a clinician.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
Standardized extract, under care.

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.