Compound or practice · Supplement
Quercetin
A flavonoid with modest blood-pressure data, a senolytic research role, and poor absorption to overcome.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade C · 1 at grade D — 2 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Blood pressureEvidence grade C
Higher doses
Smallmixed
- Senolytic (healthspan)Evidence grade D
Experimental, drug-paired
Unclearlow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Blood pressure (grade C); Senolytic (healthspan) (grade D).
- Caution with Blood-pressure medications: Additive blood-pressure lowering.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
Blood-pressure medicationsCaution
Additive blood-pressure lowering.
The evidence in words
What it is
Quercetin is a plant flavonoid found in onions and apples, studied for blood pressure, allergy, and (with fisetin) as a senolytic.
How it works
It has antioxidant, anti-inflammatory, and antihistamine actions, and in senolytic research clears senescent cells (usually paired with dasatinib in trials).
What the evidence shows
Meta-analyses show a modest blood-pressure reduction, especially at higher doses; allergy and exercise data are weaker. Its senolytic use is experimental and drug-paired. Bioavailability is poor, so formulation matters.
How to use it
500–1,000 mg/day (with absorption enhancers) for blood pressure.
Safety & interactions
Generally safe; high doses may affect kidney and drug metabolism (CYP inhibition). antihypertensives — Additive blood-pressure lowering.
Bottom line
A modest blood-pressure helper with an experimental senolytic sideline. Real but minor; absorption is the bottleneck.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 500–1,000 mg/day, absorption-enhanced.
Related reading
Entries that share this one's tags or conditions.
- Quercetin for Blood pressureEvidence grade C — Higher dosesEvidence grade C
- FisetinA flavonoid senolytic star in mice with essentially no completed human outcome data — trials are ongoing.Evidence grade D
- Quercetin for Senolytic (healthspan)Evidence grade D — Experimental, drug-pairedEvidence grade D
- Quercetin: dosage and how to take it500–1,000 mg/day, absorption-enhanced.Evidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.