Osteoarthritis pain/function: what the evidence supports

3 graded interventions for osteoarthritis pain/function, ranked by strength of evidence.

Overall grade: Grade B
Last revised: Jul 10, 2026; 3
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

2 at grade B · 1 at grade C — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
BoswelliaStandardized extracts	Evidence grade B	Moderate	mixed
UC-II (Undenatured Collagen II)40 mg/day	Evidence grade B	Moderate	mixed
ChondroitinGrade varies with quality	Evidence grade C	Small	mixed

BoswelliaEvidence grade B
Standardized extracts
Moderatemixed
UC-II (Undenatured Collagen II)Evidence grade B
40 mg/day
Moderatemixed
ChondroitinEvidence grade C
Grade varies with quality
Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Chondroitin (grade C).
Studies disagree: Boswellia (mixed agreement); UC-II (Undenatured Collagen II) (mixed agreement).

The evidence in words

The evidence map

This is the ranked evidence for osteoarthritis pain/function: every compound in the knowledge base with a graded effect, best-supported first. Grades reflect replication and effect size, not popularity or marketing.

Best-supported

Boswellia (grade B) — Standardized extracts · UC-II (Undenatured Collagen II) (grade B) — 40 mg/day

Weaker or unproven

Chondroitin (grade C) — Grade varies with quality

Goes with

BoswelliaGrade BEvidence grade B
UC-II (Undenatured Collagen II)Grade BEvidence grade B
ChondroitinGrade CEvidence grade C

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Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.