Safety · Supplement
Citicoline (CDP-Choline): side effects, safety & interactions
Well tolerated; occasional headache or GI upset.
- Overall grade
- Grade C
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Well tolerated; occasional headache or GI upset.
Interactions to respect
No major interactions are on record for Citicoline (CDP-Choline) at typical doses, but tell your clinician about everything you take.
What Citicoline (CDP-Choline) is
Citicoline (CDP-choline) supplies choline for acetylcholine and for phosphatidylcholine in cell membranes. It is used for attention, memory, and as a stroke-recovery adjunct in some regions.
The honest bottom line
The choline donor with the most reasonable cognition evidence. 250–500 mg/day for a small attention/memory nudge.
Related reading
Entries that share this one's tags or conditions.
- Bacopa Monnieri: side effects, safety & interactionsGenerally safe; GI upset (cramping, loose stools) is common, easing when taken with food. Mild sedative and thyroid-hormEvidence grade B
- Sage: side effects, safety & interactionsGenerally safe at supplemental doses; avoid high-thujone forms in pregnancy.Evidence grade C
- Alpha-GPC: side effects, safety & interactionsGenerally tolerated; the observational stroke-risk signal is unresolved and worth noting for high chronic use.Evidence grade C
- Caffeine: side effects, safety & interactionsSafe for most in moderation; excess causes anxiety, palpitations, and insomnia. Dependence and withdrawal (headache, fatEvidence grade A
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.