Safety · Supplement
Butterbur: side effects, safety & interactions
PA-containing products are hepatotoxic and carcinogenic — use only PA-free certified extracts.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
PA-containing products are hepatotoxic and carcinogenic — use only PA-free certified extracts.
Interactions to respect
No major interactions are on record for Butterbur at typical doses, but tell your clinician about everything you take.
What Butterbur is
Butterbur (Petasites hybridus) is used for migraine prevention and hay fever; only preparations free of toxic pyrrolizidine alkaloids (PA) are safe.
The honest bottom line
Genuinely effective for migraine and hay fever, but ONLY as a certified PA-free product — otherwise it can damage the liver.
Related reading
Entries that share this one's tags or conditions.
- Butterbur for MigraineEvidence grade B — PA-free onlyEvidence grade B
- Bacopa Monnieri: side effects, safety & interactionsGenerally safe; GI upset (cramping, loose stools) is common, easing when taken with food. Mild sedative and thyroid-hormEvidence grade B
- ButterburSolid evidence for migraine prevention and allergic rhinitis — but only PA-free products are safe.Evidence grade B
- Butterbur for Allergic rhinitisEvidence grade B — Antihistamine-comparable in trialsEvidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.