Evidence brief · Supplement
Yohimbine for Fat loss (fasted)
Evidence grade C — Blunted by food
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Fat loss (fasted)Evidence grade C
Blunted by food
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Fat loss (fasted) (grade C).
The evidence in words
The verdict
For fat loss (fasted), Yohimbine earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Blunted by food
How it might work
Blocking alpha-2 receptors increases fat mobilization (especially in 'stubborn' regions) and raises sympathetic tone — which also causes its side effects.
How to use it
Safety & cautions
Anxiogenic, raises heart rate and blood pressure; risky with anxiety disorders, hypertension, and MAOIs/stimulants.
Bottom line
Works for fasted fat loss and ED, but the anxiety and cardiovascular effects make it a poor fit for many. Start low, avoid with stimulants or if anxious/hypertensive.
Goes with
- YohimbineRead the full Yohimbine monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- Yohimbine for Erectile dysfunctionEvidence grade B — Real evidenceEvidence grade B
- CLA (Conjugated Linoleic Acid) for Fat lossEvidence grade D — Not meaningfulEvidence grade D
- Forskolin for Fat lossEvidence grade D — Weak, unreplicatedEvidence grade D
- Synephrine for Metabolic rate / fat lossEvidence grade C — Usually with caffeineEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.