Evidence brief · Supplement
DIM (Diindolylmethane) for Estrogen-metabolite ratio
Evidence grade B — Reliable biomarker shift
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Estrogen-metabolite ratioEvidence grade B
Reliable biomarker shift
Moderatehigh
The evidence in words
The verdict
For estrogen-metabolite ratio, DIM (Diindolylmethane) earns evidence grade B (moderate effect, high consistency) — there is real evidence here. Reliable biomarker shift
How it might work
It shifts estrogen metabolism toward less-potent metabolites and modulates androgen and detox pathways.
How to use it
100–200 mg/day.
Safety & cautions
Generally tolerated; can alter drug metabolism and hormone levels.
Bottom line
A real estrogen-metabolism modulator with thin clinical proof. Reasonable to trial for hormonal skin/balance goals.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 100–200 mg/day.
Goes with
- DIM (Diindolylmethane)Read the full DIM (Diindolylmethane) monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- DIM (Diindolylmethane) for Hormonal acne / lesionsEvidence grade C — PreliminaryEvidence grade C
- Calcium D-Glucarate for Estrogen / toxin clearanceEvidence grade D — Mechanistic onlyEvidence grade D
- DIM (Diindolylmethane): dosage and how to take it100–200 mg/day.Evidence grade C
- DIM (Diindolylmethane): side effects, safety & interactionsGenerally tolerated; can alter drug metabolism and hormone levels.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.