Medication · Medication
Digoxin
A narrow-therapeutic-window heart drug used in some heart-failure and rhythm settings.
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A medication reference built from the interaction graph. It is not prescribing information — the label and your prescriber are.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Caution with St. John's Wort: St John's Wort lowers digoxin levels via P-glycoprotein induction.
- Caution with Hawthorn: Hawthorn's cardiac activity is additive with digoxin — coordinate closely.
- Caution with Potassium: Potassium imbalance (either way) alters digoxin toxicity — a monitored relationship.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
St. John's WortCaution
St John's Wort lowers digoxin levels via P-glycoprotein induction.
HawthornCaution
Hawthorn's cardiac activity is additive with digoxin — coordinate closely.
PotassiumCaution
Potassium imbalance (either way) alters digoxin toxicity — a monitored relationship.
The evidence in words
What it is
A narrow-therapeutic-window heart drug used in some heart-failure and rhythm settings.
How it works
It strengthens heart contraction and slows conduction; its toxicity is exquisitely sensitive to potassium and to other cardioactive compounds.
What it's used for
Heart failure, atrial fibrillation rate control.
Supplement & drug interactions
Digoxin has 3 documented interactions mapped below and in the interactions graph. Potassium imbalance (in either direction) alters digoxin toxicity, so anything affecting potassium matters; hawthorn adds cardiac effects, and St John's Wort lowers digoxin levels. A drug where interactions can be genuinely dangerous — tight prescriber oversight.
The rule
This is a medication reference for spotting interactions, not dosing advice. Every change to a supplement stack around a prescription belongs with the person who prescribes it.
Related reading
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Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.