Medication · Medication
Alcohol
Ethanol — a CNS depressant and hepatotoxin with a broad interaction footprint.
- Last revised
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- graded outcomes
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- references listed
A medication reference built from the interaction graph. It is not prescribing information — the label and your prescriber are.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Caution with Kava: Additive sedation and compounded liver stress.
- Caution with Benzodiazepines: Additive CNS and respiratory depression — a leading cause of sedative overdose.
- Caution with Opioids: Respiratory depression multiplies — a frequently fatal combination.
- Caution with Valerian: Additive sedation — don't combine.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
KavaCaution
Additive sedation and compounded liver stress.
BenzodiazepinesCaution
Additive CNS and respiratory depression — a leading cause of sedative overdose.
OpioidsCaution
Respiratory depression multiplies — a frequently fatal combination.
ValerianCaution
Additive sedation — don't combine.
The evidence in words
What it is
Ethanol — a CNS depressant and hepatotoxin with a broad interaction footprint.
How it works
It depresses the central nervous system and stresses the liver, compounding both sedatives and hepatotoxic compounds.
What it's used for
n/a — this page exists because of its interactions.
Supplement & drug interactions
Alcohol has 4 documented interactions mapped below and in the interactions graph. The additive-sedation and liver themes: alcohol with benzodiazepines or opioids risks fatal respiratory depression, and with kava (or high-dose green tea extract, niacin) compounds liver stress. It also depletes B vitamins and magnesium over time.
The rule
This is a medication reference for spotting interactions, not dosing advice. Every change to a supplement stack around a prescription belongs with the person who prescribes it.
Related reading
Entries that share this one's tags or conditions.
- BenzodiazepinesSedative anti-anxiety and sleep drugs.Evidence grade A
- GrapefruitNot a drug — a food, but a potent and long-lasting inhibitor of the CYP3A4 enzyme in the gut, which is why it has a drug-like interaction profile.Evidence grade A
- OpioidsStrong pain-relievers that also depress breathing.Evidence grade A
- ADHD StimulantsPrescription stimulants for attention-deficit/hyperactivity disorder.Evidence grade A
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.