Compound or practice · Nutrition
Zinc-Carnosine
A gut-lining complex with modest evidence for gastric protection and 'leaky gut' repair.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
3 at grade C — 3 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Gastric-ulcer healingEvidence grade C
Often adjunctive
Moderatemixed
- Gut-barrier protectionEvidence grade C
NSAID damage
Smallmixed
Conditions
How the entry reads its effect on diagnosed conditions: the direction first, then the grade. Never a substitute for the person who treats you.
- Gastritis / gut-barrier May improveEvidence grade CAdjunctGrade C
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Gastric-ulcer healing (grade C); Gut-barrier protection (grade C).
- Watch with Copper: Chronic high zinc intake can lower copper.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
CopperDepletes a nutrient
Chronic high zinc intake can lower copper.
The evidence in words
What it is
Zinc-carnosine (polaprezinc) is a chelate used in Japan for gastric ulcers and gut-lining support.
How it works
It adheres to damaged mucosa, providing zinc locally for repair and antioxidant defense.
What the evidence shows
Reasonable evidence for supporting gastric-ulcer healing (often with standard therapy) and reducing NSAID-induced gut-barrier damage; broader 'leaky gut' claims are extrapolated. Safe.
How to use it
75 mg/day (delivering zinc + L-carnosine), often split.
Safety & interactions
Generally safe; counts toward total zinc intake (watch copper with chronic high use). Copper — Chronic high zinc intake can lower copper.
Bottom line
A targeted gut-lining supplement with real gastric-protection evidence. 75 mg/day; mind total zinc.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 75 mg/day, split.
Related reading
Entries that share this one's tags or conditions.
- DGL (Licorice)Deglycyrrhizinated licorice for heartburn and ulcers — the 'DGL' form removes licorice's blood-pressure danger.Evidence grade C
- Zinc-Carnosine for Gastric-ulcer healingEvidence grade C — Often adjunctiveEvidence grade C
- Zinc-Carnosine for Gastritis / gut-barrierEvidence grade C — AdjunctEvidence grade C
- Zinc-Carnosine for Gut-barrier protectionEvidence grade C — NSAID damageEvidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.