Compound or practice · Nutrition
DGL (Licorice)
Deglycyrrhizinated licorice for heartburn and ulcers — the 'DGL' form removes licorice's blood-pressure danger.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
3 at grade C — 3 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Dyspepsia / refluxEvidence grade C
Symptom relief
Smallmixed
- Mouth/peptic ulcersEvidence grade C
Older data
Smallmixed
Conditions
How the entry reads its effect on diagnosed conditions: the direction first, then the grade. Never a substitute for the person who treats you.
- Functional dyspepsia May improveEvidence grade CDGL formGrade C
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Dyspepsia / reflux (grade C); Mouth/peptic ulcers (grade C).
The evidence in words
What it is
DGL is licorice with glycyrrhizin removed, used for dyspepsia, reflux, and mouth/gut ulcers.
How it works
It supports mucosal defense and mucus production in the stomach lining; removing glycyrrhizin avoids licorice's mineralocorticoid effects.
What the evidence shows
Older and small studies support symptomatic relief in dyspepsia and canker/peptic ulcers. Crucially, ordinary (glycyrrhizin-containing) licorice raises blood pressure and lowers potassium — DGL avoids this.
How to use it
Chewable DGL before meals for reflux/dyspepsia.
Safety & interactions
DGL is safe; regular licorice is not (hypertension, hypokalemia) — use the DGL form.
Bottom line
A useful, gentle option for heartburn and ulcers — but only as DGL. Never use high-glycyrrhizin licorice for this.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- Chewable DGL before meals.
Related reading
Entries that share this one's tags or conditions.
- DGL (Licorice) for Dyspepsia / refluxEvidence grade C — Symptom reliefEvidence grade C
- DGL (Licorice) for Functional dyspepsiaEvidence grade C — DGL formEvidence grade C
- DGL (Licorice) for Mouth/peptic ulcersEvidence grade C — Older dataEvidence grade C
- DGL (Licorice): dosage and how to take itChewable DGL before meals.Evidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.