Osteoarthritis: what the evidence supports

5 graded interventions for osteoarthritis, ranked by strength of evidence.

Overall grade: Grade B
Last revised: Jul 10, 2026; 5
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

3 at grade B · 2 at grade C — 5 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Curcumin (Turmeric)Bioavailable forms	Evidence grade B	Unclear	mixed
Collagen PeptidesPain/function	Evidence grade B	Unclear	mixed
BoswelliaReasonable RCT support	Evidence grade B	Unclear	mixed
GlucosamineTrial for 8–12 weeks	Evidence grade C	Unclear	mixed
Hyaluronic Acid (Oral)Knee comfort	Evidence grade C	Unclear	mixed

Curcumin (Turmeric)Evidence grade B
Bioavailable forms
Unclearmixed
Collagen PeptidesEvidence grade B
Pain/function
Unclearmixed
BoswelliaEvidence grade B
Reasonable RCT support
Unclearmixed
GlucosamineEvidence grade C
Trial for 8–12 weeks
Unclearmixed
Hyaluronic Acid (Oral)Evidence grade C
Knee comfort
Unclearmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Glucosamine (grade C); Hyaluronic Acid (Oral) (grade C).
Studies disagree: Curcumin (Turmeric) (mixed agreement); Collagen Peptides (mixed agreement); Boswellia (mixed agreement).

The evidence in words

The evidence map

This is the ranked evidence for osteoarthritis: every compound in the knowledge base with a graded effect, best-supported first. Grades reflect replication and effect size, not popularity or marketing.

Best-supported

Curcumin (Turmeric) (grade B) — Bioavailable forms · Collagen Peptides (grade B) — Pain/function · Boswellia (grade B) — Reasonable RCT support

Weaker or unproven

Glucosamine (grade C) — Trial for 8–12 weeks · Hyaluronic Acid (Oral) (grade C) — Knee comfort

Goes with

Curcumin (Turmeric)Grade BEvidence grade B
Collagen PeptidesGrade BEvidence grade B
BoswelliaGrade BEvidence grade B
GlucosamineGrade CEvidence grade C
Hyaluronic Acid (Oral)Grade CEvidence grade C

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Anxiety: what the evidence supports6 graded interventions for anxiety, ranked by strength of evidence.Evidence grade B
Benign prostatic hyperplasia: what the evidence supports3 graded interventions for benign prostatic hyperplasia, ranked by strength of evidence.Evidence grade C

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.