Compound or practice · Supplement

Tongkat Ali

The testosterone-support herb with the least-bad evidence — modest free-T and stress signals, best in the stressed or older.

Overall grade
Grade C
Last revised
3
graded outcomes
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

3 at grade C — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Free testosteroneEvidence grade C

    Larger in stressed/older

    Smallmixed

  • Stress / cortisolEvidence grade C

    Modest

    Smallmixed

  • LibidoEvidence grade C

    Subjective

    Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Free testosterone (grade C); Stress / cortisol (grade C); Libido (grade C).

Interactions

Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.

  • ZincWorks together

    Free-T support assumes zinc sufficiency.

  • BoronWorks together

    Common free-testosterone support stack.

The evidence in words

What it is

Tongkat ali (Eurycoma longifolia) is a standardized root extract (often to eurycomanone) used for testosterone, libido, and stress.

How it works

It appears to lower sex-hormone-binding globulin (freeing testosterone) and reduce cortisol, plausibly improving the testosterone-to-cortisol ratio under stress.

What the evidence shows

Small trials show modest increases in free testosterone, improved stress markers, and libido, with larger effects in stressed, older, or hypogonadal men than in healthy young men. It is the best-supported of a weak category — an experiment with an end date, not a default.

How to use it

200–400 mg/day of a standardized extract; assess over 4–8 weeks.

Safety & interactions

Generally tolerated; long-term safety and heavy-metal contamination of poor products are concerns — buy tested brands. Zinc — Free-T support assumes zinc sufficiency. Boron — Common free-testosterone support stack.

Bottom line

If you're going to trial a testosterone-support herb, this is the one — 200–400 mg standardized, most likely to help if you're stressed or older. Gate the trial on a lab and buy a tested product.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
200–400 mg/day standardized, 4–8 week trial.

Goes with

  • ZincFree-T support assumes zinc sufficiency.Evidence grade B
  • BoronCommon free-testosterone support stack.Evidence grade C

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.