Safety · Supplement
Pregnenolone: side effects, safety & interactions
Unpredictable hormonal effects; not for casual use; banned in some sport contexts.
- Overall grade
- Grade D
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Unpredictable hormonal effects; not for casual use; banned in some sport contexts.
Interactions to respect
No major interactions are on record for Pregnenolone at typical doses, but tell your clinician about everything you take.
What Pregnenolone is
Pregnenolone is the upstream precursor to all steroid hormones, marketed for memory, mood, and 'anti-aging.'
The honest bottom line
A hormone precursor with thin evidence and unpredictable downstream effects. Not a supplement to self-prescribe.
Related reading
Entries that share this one's tags or conditions.
- DHEA: side effects, safety & interactionsHormonal side effects (acne, hair changes, and hormone-sensitive-cancer concerns); it is not a benign supplement. BannedEvidence grade C
- Centrophenoxine: side effects, safety & interactionsGenerally tolerated.Evidence grade D
- PregnenoloneThe 'grandmother' steroid hormone sold for memory and mood — it IS a hormone, and the human data are thin.Evidence grade D
- Pregnenolone for Memory / moodEvidence grade D — Weak, oldEvidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.