Interaction · Supplement
Kanna (Sceletium tortuosum) + SSRIs / SNRIs: use with caution
SSRI-like reuptake inhibition — serotonin-syndrome risk; don't combine.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Watch with Kanna (Sceletium tortuosum): About Kanna (Sceletium tortuosum)
The evidence in words
The interaction
Kanna (Sceletium tortuosum) and SSRIs / SNRIs — a caution interaction. SSRI-like reuptake inhibition — serotonin-syndrome risk; don't combine.
What to do
Do not combine these casually. The interaction can matter clinically — bring it to the prescriber who manages the medication before stacking them.
About Kanna (Sceletium tortuosum)
Kanna is a succulent traditionally chewed for mood; the standardized extract Zembrin is used for stress and cognition.
The bigger picture
Supplement–drug and supplement–supplement interactions are the reason a stack should be read as a system, not a list. This platform's interactions graph maps them; the medication side always belongs with the person who prescribes it.
Related reading
Entries that share this one's tags or conditions.
- L-Tryptophan / 5-HTP + SSRIs / SNRIs: use with cautionSerotonin-syndrome risk — do not combine without a prescriber.Evidence grade B
- Melatonin + SSRIs / SNRIs: use with cautionSome SSRIs (fluvoxamine) spike melatonin levels — microdose or skip.Evidence grade B
- Methylene Blue + SSRIs / SNRIs: use with cautionMAO inhibition + serotonergic drugs = serotonin-syndrome risk. Do not combine.Evidence grade B
- Mucuna Pruriens (L-Dopa) + SSRIs / SNRIs: use with cautionSerotonergic/MAOI combinations risk serious reactions.Evidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.