Supplements for pms

3 compounds relevant to pms, ranked by overall evidence grade.

Overall grade: Grade B
Last revised: Jul 10, 2026; 3
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

2 at grade B · 1 at grade C — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Vitamin B6A cofactor for neurotransmitter and amino-acid metabolism; genuinely useful for pregnancy nausea and PMS, toxic if chronically megadosed.	Evidence grade B	Unclear	mixed
Vitex (Chasteberry)One of the better-supported botanicals for PMS and cyclical breast pain, working through prolactin.	Evidence grade B	Unclear	mixed
Evening Primrose Oil (GLA)A GLA source popular for PMS, breast pain, and eczema — mostly modest or null on rigorous review.	Evidence grade C	Unclear	mixed

Vitamin B6Evidence grade B
A cofactor for neurotransmitter and amino-acid metabolism; genuinely useful for pregnancy nausea and PMS, toxic if chronically megadosed.
Unclearmixed
Vitex (Chasteberry)Evidence grade B
One of the better-supported botanicals for PMS and cyclical breast pain, working through prolactin.
Unclearmixed
Evening Primrose Oil (GLA)Evidence grade C
A GLA source popular for PMS, breast pain, and eczema — mostly modest or null on rigorous review.
Unclearmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Evening Primrose Oil (GLA) (grade C).
Studies disagree: Vitamin B6 (mixed agreement); Vitex (Chasteberry) (mixed agreement).

The evidence in words

The shortlist

Every compound in the knowledge base tagged to pms, ordered by how strong its overall evidence is. Start at the top; the grade is the honest filter.

Worth considering first

Vitamin B6 (B) — A cofactor for neurotransmitter and amino-acid metabolism; genuinely useful for pregnancy nausea and PMS, toxic if chronically megadosed. · Vitex (Chasteberry) (B) — One of the better-supported botanicals for PMS and cyclical breast pain, working through prolactin.

Lower-evidence options

Evening Primrose Oil (GLA) (C) — A GLA source popular for PMS, breast pain, and eczema — mostly modest or null on rigorous review.

Goes with

Vitamin B6Grade BEvidence grade B
Vitex (Chasteberry)Grade BEvidence grade B
Evening Primrose Oil (GLA)Grade CEvidence grade C

Entries that share this one's tags or conditions.

Evening Primrose Oil (GLA) for PMSEvidence grade C — InconsistentEvidence grade C
Vitex (Chasteberry) for PMSEvidence grade B — Across cyclesEvidence grade B
Evening Primrose Oil (GLA) for EczemaEvidence grade D — Reviews nullEvidence grade D
Evening Primrose Oil (GLA) for PMS / breast painEvidence grade C — MixedEvidence grade C

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.