Evening Primrose Oil (GLA) for PMS / breast pain

Evidence grade C — Mixed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade C — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
PMS / breast painMixed	Evidence grade C	Small	mixed

Read off the same rows as above. Nothing here is added that the entry does not itself record.

For pms / breast pain, Evening Primrose Oil (GLA) earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Mixed

GLA feeds anti-inflammatory prostaglandin pathways.

Standardized GLA dose daily, given several weeks.

Generally safe; mild antiplatelet action; caution with seizure threshold in some.

Popular for PMS and skin, weak on hard evidence. Low-risk to trial; temper expectations.

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Evening Primrose Oil (GLA)Read the full Evening Primrose Oil (GLA) monographEvidence grade C

Entries that share this one's tags or conditions.

Evening Primrose Oil (GLA) for PMSEvidence grade C — InconsistentEvidence grade C
Evening Primrose Oil (GLA) for EczemaEvidence grade D — Reviews nullEvidence grade D
Vitex (Chasteberry) for PMSEvidence grade B — Across cyclesEvidence grade B
DIM (Diindolylmethane) for Estrogen-metabolite ratioEvidence grade B — Reliable biomarker shiftEvidence grade B

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.