Supplements for libido

10 compounds relevant to libido, ranked by overall evidence grade.

Overall grade: Grade C
Last revised: Jul 10, 2026; 10
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

6 at grade C · 4 at grade D — 10 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Panax GinsengA classic tonic with scattered small wins for fatigue, cognition, and erectile function — rarely dramatic, watch drug interactions.	Evidence grade C	Unclear	mixed
Tongkat AliThe testosterone-support herb with the least-bad evidence — modest free-T and stress signals, best in the stressed or older.	Evidence grade C	Unclear	mixed
MacaA Peruvian root that improves libido without moving hormones — real for desire, not a testosterone booster.	Evidence grade C	Unclear	mixed
FenugreekA libido herb with reasonable sexual-function data and inconsistent testosterone claims — the effect people feel is desire, not androgens.	Evidence grade C	Unclear	mixed
L-ArginineThe direct nitric-oxide precursor that mostly loses to citrulline because the gut destroys it first.	Evidence grade C	Unclear	mixed
YohimbineA fasted-cardio fat-loss aid and erectile-function agent — effective but genuinely anxiogenic and blood-pressure-raising.	Evidence grade C	Unclear	mixed
Horny Goat WeedA libido herb whose active icariin is a weak PDE5 inhibitor in theory and essentially untested in humans.	Evidence grade D	Unclear	mixed
Tribulus TerrestrisA staple 'testosterone booster' that reliably does not raise testosterone — some libido effect at most.	Evidence grade D	Unclear	mixed
CistancheA desert 'tonic' herb for vigor and libido with mostly traditional and preclinical backing.	Evidence grade D	Unclear	mixed
Muira PuamaAn Amazonian 'potency wood' for libido with almost no controlled evidence behind the tradition.	Evidence grade D	Unclear	mixed

Panax GinsengEvidence grade C
A classic tonic with scattered small wins for fatigue, cognition, and erectile function — rarely dramatic, watch drug interactions.
Unclearmixed
Tongkat AliEvidence grade C
The testosterone-support herb with the least-bad evidence — modest free-T and stress signals, best in the stressed or older.
Unclearmixed
MacaEvidence grade C
A Peruvian root that improves libido without moving hormones — real for desire, not a testosterone booster.
Unclearmixed
FenugreekEvidence grade C
A libido herb with reasonable sexual-function data and inconsistent testosterone claims — the effect people feel is desire, not androgens.
Unclearmixed
L-ArginineEvidence grade C
The direct nitric-oxide precursor that mostly loses to citrulline because the gut destroys it first.
Unclearmixed
YohimbineEvidence grade C
A fasted-cardio fat-loss aid and erectile-function agent — effective but genuinely anxiogenic and blood-pressure-raising.
Unclearmixed
Horny Goat WeedEvidence grade D
A libido herb whose active icariin is a weak PDE5 inhibitor in theory and essentially untested in humans.
Unclearmixed
Tribulus TerrestrisEvidence grade D
A staple 'testosterone booster' that reliably does not raise testosterone — some libido effect at most.
Unclearmixed
CistancheEvidence grade D
A desert 'tonic' herb for vigor and libido with mostly traditional and preclinical backing.
Unclearmixed
Muira PuamaEvidence grade D
An Amazonian 'potency wood' for libido with almost no controlled evidence behind the tradition.
Unclearmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Panax Ginseng (grade C); Tongkat Ali (grade C); Maca (grade C); Fenugreek (grade C); L-Arginine (grade C); Yohimbine (grade C); Horny Goat Weed (grade D); Tribulus Terrestris (grade D); Cistanche (grade D); Muira Puama (grade D).

The evidence in words

The shortlist

Every compound in the knowledge base tagged to libido, ordered by how strong its overall evidence is. Start at the top; the grade is the honest filter.

Worth considering first

Nothing here clears grade B — treat this whole category as experimental.

Lower-evidence options

Panax Ginseng (C) — A classic tonic with scattered small wins for fatigue, cognition, and erectile function — rarely dramatic, watch drug interactions. · Tongkat Ali (C) — The testosterone-support herb with the least-bad evidence — modest free-T and stress signals, best in the stressed or older. · Maca (C) — A Peruvian root that improves libido without moving hormones — real for desire, not a testosterone booster. · Fenugreek (C) — A libido herb with reasonable sexual-function data and inconsistent testosterone claims — the effect people feel is desire, not androgens. · L-Arginine (C) — The direct nitric-oxide precursor that mostly loses to citrulline because the gut destroys it first. · Yohimbine (C) — A fasted-cardio fat-loss aid and erectile-function agent — effective but genuinely anxiogenic and blood-pressure-raising. · Horny Goat Weed (D) — A libido herb whose active icariin is a weak PDE5 inhibitor in theory and essentially untested in humans. · Tribulus Terrestris (D) — A staple 'testosterone booster' that reliably does not raise testosterone — some libido effect at most. · Cistanche (D) — A desert 'tonic' herb for vigor and libido with mostly traditional and preclinical backing. · Muira Puama (D) — An Amazonian 'potency wood' for libido with almost no controlled evidence behind the tradition.

Goes with

Panax GinsengGrade CEvidence grade C
Tongkat AliGrade CEvidence grade C
MacaGrade CEvidence grade C
FenugreekGrade CEvidence grade C
L-ArginineGrade CEvidence grade C
YohimbineGrade CEvidence grade C
Horny Goat WeedGrade DEvidence grade D
Tribulus TerrestrisGrade DEvidence grade D

Entries that share this one's tags or conditions.

Tongkat Ali for LibidoEvidence grade C — SubjectiveEvidence grade C
Tribulus Terrestris for LibidoEvidence grade C — Hormone-independentEvidence grade C
CistancheA desert 'tonic' herb for vigor and libido with mostly traditional and preclinical backing.Evidence grade D
Cistanche for Vigor / libidoEvidence grade D — Traditional/preclinicalEvidence grade D

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.