Magnolia Bark for Stress / cortisol

Evidence grade C — Often combined

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade C — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Stress / cortisolOften combined	Evidence grade C	Small	mixed

Read off the same rows as above. Nothing here is added that the entry does not itself record.

For stress / cortisol, Magnolia Bark earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Often combined

GABAergic and cortisol-modulating actions; honokiol has anxiolytic activity in models.

Standardized honokiol/magnolol extract, evening for sleep.

Generally safe short-term; additive sedation.

An early-evidence anti-stress and sleep botanical. Reasonable low-risk trial, often in blends.

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Entries that share this one's tags or conditions.

Magnolia Bark for SleepEvidence grade C — EarlyEvidence grade C
Kava for AnxietyEvidence grade B — Meta-analytic vs placeboEvidence grade B
Kava for Liver injury (rare)Evidence grade C — Extract/cultivar dependentEvidence grade C
Lemon Balm for Acute anxiety / stressEvidence grade C — AcuteEvidence grade C

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.