Evidence brief · Supplement

Kava for Anxiety

Evidence grade B — Meta-analytic vs placebo

Overall grade
Grade B
Last revised
1
graded outcome
0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade B — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • AnxietyEvidence grade B

    Meta-analytic vs placebo

    Moderatemixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Studies disagree: Anxiety (mixed agreement).

The evidence in words

The verdict

For anxiety, Kava earns evidence grade B (moderate effect, mixed consistency) — there is real evidence here. Meta-analytic vs placebo

How it might work

Kavalactones modulate GABA and other pathways, producing anxiolysis without the dependence profile of benzodiazepines.

How to use it

Standardized to ~70–250 mg kavalactones/day, short-term, water-based noble-cultivar products.

Safety & cautions

Liver-toxicity risk (rare) — avoid with alcohol, hepatotoxic drugs, or existing liver disease; additive with sedatives.

Bottom line

A genuinely effective short-term anxiety herb with a serious liver caveat. Use water-based noble kava, never with alcohol or sedatives, and not long-term.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
70–250 mg kavalactones/day, water-based, short-term.

Goes with

  • KavaRead the full Kava monographEvidence grade B

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised . A grade is this entry's reading of the evidence, not medical advice.