Evidence brief · Supplement
Horse Chestnut for Chronic venous insufficiency
Evidence grade B — Cochrane-supported
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Chronic venous insufficiencyEvidence grade B
Cochrane-supported
Moderatehigh
The evidence in words
The verdict
For chronic venous insufficiency, Horse Chestnut earns evidence grade B (moderate effect, high consistency) — there is real evidence here. Cochrane-supported
How it might work
Aescin improves venous tone and reduces capillary leakage, cutting fluid accumulation in the legs.
How to use it
Standardized to ~50 mg aescin twice daily.
Safety & cautions
Standardized extract is safe; raw horse chestnut is toxic; mild antiplatelet and glucose effects.
Bottom line
One of the better-evidenced vein supplements for leg swelling and heaviness. Use standardized aescin — never raw seeds.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- ~50 mg aescin twice daily.
Goes with
- Horse ChestnutRead the full Horse Chestnut monographEvidence grade B
Related reading
Entries that share this one's tags or conditions.
- Diosmin / Hesperidin for Chronic venous insufficiencyEvidence grade B — Well supportedEvidence grade B
- Diosmin / Hesperidin for Hemorrhoid flaresEvidence grade B — Acute reliefEvidence grade B
- Horse Chestnut: dosage and how to take it~50 mg aescin twice daily.Evidence grade B
- Horse Chestnut: side effects, safety & interactionsStandardized extract is safe; raw horse chestnut is toxic; mild antiplatelet and glucose effects.Evidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.