Evidence brief · Supplement
Diosmin / Hesperidin for Chronic venous insufficiency
Evidence grade B — Well supported
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Chronic venous insufficiencyEvidence grade B
Well supported
Moderatehigh
The evidence in words
The verdict
For chronic venous insufficiency, Diosmin / Hesperidin earns evidence grade B (moderate effect, high consistency) — there is real evidence here. Well supported
How it might work
These flavonoids improve venous tone, lymphatic drainage, and capillary resistance, reducing swelling and inflammation.
How to use it
Micronized diosmin/hesperidin (e.g., 1,000 mg/day; higher acutely for hemorrhoids).
Safety & cautions
Generally safe; mild GI effects.
Bottom line
Genuinely effective for vein symptoms and hemorrhoids — a European standard. Micronized purified flavonoid fraction is the studied form.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- Micronized 1,000 mg/day; higher acutely.
Goes with
- Diosmin / HesperidinRead the full Diosmin / Hesperidin monographEvidence grade B
Related reading
Entries that share this one's tags or conditions.
- Diosmin / Hesperidin for Hemorrhoid flaresEvidence grade B — Acute reliefEvidence grade B
- Horse Chestnut for Chronic venous insufficiencyEvidence grade B — Cochrane-supportedEvidence grade B
- Diosmin / Hesperidin: dosage and how to take itMicronized 1,000 mg/day; higher acutely.Evidence grade B
- Diosmin / Hesperidin: side effects, safety & interactionsGenerally safe; mild GI effects.Evidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.