Safety · Supplement
Horse Chestnut: side effects, safety & interactions
Standardized extract is safe; raw horse chestnut is toxic; mild antiplatelet and glucose effects.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Standardized extract is safe; raw horse chestnut is toxic; mild antiplatelet and glucose effects.
Interactions to respect
Anticoagulants (warfarin) — Mild antiplatelet — additive bleeding risk.
What Horse Chestnut is
Horse chestnut seed extract (aescin) is used for chronic venous insufficiency and varicose-vein symptoms.
The honest bottom line
One of the better-evidenced vein supplements for leg swelling and heaviness. Use standardized aescin — never raw seeds.
Related reading
Entries that share this one's tags or conditions.
- Diosmin / Hesperidin: side effects, safety & interactionsGenerally safe; mild GI effects.Evidence grade B
- Cinnamon: side effects, safety & interactionsHigh-dose cassia coumarin can stress the liver; additive glucose lowering with diabetes drugs.Evidence grade C
- Grape Seed Extract: side effects, safety & interactionsGenerally safe; mild antiplatelet action.Evidence grade C
- Green Tea Extract (EGCG): side effects, safety & interactionsBrewed tea is safe. Concentrated extracts carry a rare hepatotoxicity risk; avoid high fasted doses.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.