Evidence brief · Supplement
Ergothioneine for Mortality association
Evidence grade C — Observational
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Mortality associationEvidence grade C
Observational
Unclearmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Mortality association (grade C).
The evidence in words
The verdict
For mortality association, Ergothioneine earns evidence grade C (unclear effect, mixed consistency) — the evidence is limited or mixed. Observational
How it might work
It accumulates in cells under oxidative stress and scavenges reactive species; the dedicated transporter implies a physiological role.
How to use it
Safety & cautions
Appears very safe; naturally consumed in mushrooms.
Bottom line
A biologically special antioxidant with intriguing longevity associations, awaiting outcome trials. Eating mushrooms is the easy, evidence-adjacent way to get it.
Goes with
- ErgothioneineRead the full Ergothioneine monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- Chaga for Immunity / antioxidant (humans)Evidence grade D — No trialsEvidence grade D
- Ergothioneine: side effects, safety & interactionsAppears very safe; naturally consumed in mushrooms.Evidence grade C
- Sulforaphane for Metabolic markersEvidence grade C — EarlyEvidence grade C
- Sulforaphane for Nrf2 / detox biomarkersEvidence grade B — ReliableEvidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.