Evidence brief · Supplement
DMAE for Cognition / mood
Evidence grade D — Mixed
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Cognition / moodEvidence grade D
Mixed
Triviallow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Cognition / mood (grade D).
The evidence in words
The verdict
For cognition / mood, DMAE earns evidence grade D (trivial effect, low consistency) — the evidence does not support the claim. Mixed
How it might work
A putative acetylcholine precursor with antioxidant activity; the cholinergic route is debated.
How to use it
Safety & cautions
Generally tolerated; avoid in pregnancy given developmental concerns.
Bottom line
Weak for cognition; the better evidence is topical/cosmetic. Skip it as a nootropic.
Goes with
- DMAERead the full DMAE monographEvidence grade D
Related reading
Entries that share this one's tags or conditions.
- Aniracetam for Cognition / moodEvidence grade D — Mostly preclinicalEvidence grade D
- CentrophenoxineAn old cholinergic anti-aging compound with dated cognitive-decline data.Evidence grade D
- Centrophenoxine for Cognition (elderly)Evidence grade D — DatedEvidence grade D
- DMAE: side effects, safety & interactionsGenerally tolerated; avoid in pregnancy given developmental concerns.Evidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.