Evidence brief · Supplement

Citicoline (CDP-Choline) for Attention / memory

Evidence grade C — Modest

Overall grade
Grade C
Last revised
1
graded outcome
0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade C — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Attention / memoryEvidence grade C

    Modest

    Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Attention / memory (grade C).

The evidence in words

The verdict

For attention / memory, Citicoline (CDP-Choline) earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Modest

How it might work

It boosts acetylcholine synthesis and membrane phospholipid turnover, supporting cholinergic neurotransmission and neuronal membrane integrity.

How to use it

250–500 mg/day, sometimes split. Often paired with caffeine.

Safety & cautions

Well tolerated; occasional headache or GI upset.

Bottom line

The choline donor with the most reasonable cognition evidence. 250–500 mg/day for a small attention/memory nudge.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
250–500 mg/day.

Goes with

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised . A grade is this entry's reading of the evidence, not medical advice.