Medication · Medication
Diuretics
'Water pills' that increase fluid and electrolyte excretion.
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A medication reference built from the interaction graph. It is not prescribing information — the label and your prescriber are.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Caution with Potassium: Loop/thiazide diuretics lower potassium, but potassium-sparing diuretics do the reverse — know which you take.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
PotassiumCaution
Loop/thiazide diuretics lower potassium, but potassium-sparing diuretics do the reverse — know which you take.
MagnesiumDepletes a nutrient
Loop and thiazide diuretics waste magnesium — a common cause of low levels.
ZincDepletes a nutrient
Thiazide diuretics increase urinary zinc loss over time.
The evidence in words
What it is
'Water pills' that increase fluid and electrolyte excretion.
How it works
Depending on the type, they waste or spare specific electrolytes — the key to their supplement interactions.
What it's used for
Hypertension, heart failure, edema.
Supplement & drug interactions
Diuretics has 3 documented interactions mapped below and in the interactions graph. Loop and thiazide diuretics waste magnesium, potassium, and zinc (deficiencies to watch); potassium-sparing diuretics do the opposite, so potassium supplements then risk dangerous highs. Which diuretic you take flips the advice.
Nutrient depletions
Drug-induced nutrient depletion is real and under-recognized: Diuretics can lower Magnesium, Zinc. Loop and thiazide diuretics waste magnesium — a common cause of low levels. Thiazide diuretics increase urinary zinc loss over time.
The rule
This is a medication reference for spotting interactions, not dosing advice. Every change to a supplement stack around a prescription belongs with the person who prescribes it.
Related reading
Entries that share this one's tags or conditions.
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Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.