Weight loss: what the evidence supports

3 graded interventions for weight loss, ranked by strength of evidence.

Overall grade: Grade D
Last revised: Jul 10, 2026; 3
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

3 at grade D — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Apple Cider VinegarNegligible	Evidence grade D	Trivial	low
Green Coffee ExtractKey study retracted	Evidence grade D	Trivial	low
Garcinia Cambogia (HCA)Not meaningful	Evidence grade D	Trivial	high

Apple Cider VinegarEvidence grade D
Negligible
Triviallow
Green Coffee ExtractEvidence grade D
Key study retracted
Triviallow
Garcinia Cambogia (HCA)Evidence grade D
Not meaningful
Trivialhigh

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Apple Cider Vinegar (grade D); Green Coffee Extract (grade D); Garcinia Cambogia (HCA) (grade D).

The evidence in words

The evidence map

This is the ranked evidence for weight loss: every compound in the knowledge base with a graded effect, best-supported first. Grades reflect replication and effect size, not popularity or marketing.

Best-supported

No intervention here reaches grade A or B — an honest reflection of how thin the evidence for weight loss still is.

Weaker or unproven

Apple Cider Vinegar (grade D) — Negligible · Green Coffee Extract (grade D) — Key study retracted · Garcinia Cambogia (HCA) (grade D) — Not meaningful

Goes with

Apple Cider VinegarGrade DEvidence grade C
Green Coffee ExtractGrade DEvidence grade D
Garcinia Cambogia (HCA)Grade DEvidence grade D

Entries that share this one's tags or conditions.

Allergic rhinitis: what the evidence supports3 graded interventions for allergic rhinitis, ranked by strength of evidence.Evidence grade B
Antibiotic-associated diarrhea: what the evidence supports2 graded interventions for antibiotic-associated diarrhea, ranked by strength of evidence.Evidence grade B
Anxiety: what the evidence supports6 graded interventions for anxiety, ranked by strength of evidence.Evidence grade B
Apple Cider Vinegar for Weight lossEvidence grade D — NegligibleEvidence grade D

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.