Safety · Supplement
Thiamine (B1): side effects, safety & interactions
Very safe; excess is excreted. The risk is missing deficiency, not the supplement.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Very safe; excess is excreted. The risk is missing deficiency, not the supplement.
Interactions to respect
No major interactions are on record for Thiamine (B1) at typical doses, but tell your clinician about everything you take.
What Thiamine (B1) is
Thiamine is a water-soluble vitamin with unusually small body stores, so deficiency develops quickly under high-carbohydrate loads, alcohol-use disorder, or malnutrition. Benfotiamine is a fat-soluble derivative with better tissue uptake.
The honest bottom line
A quiet essential with a dramatic deficiency. Most people get enough; heavy drinkers, the malnourished, and bariatric-surgery patients should supplement — and acute deficiency is an ER matter, not a capsule.
Related reading
Entries that share this one's tags or conditions.
- Iodine: side effects, safety & interactionsHigh doses can induce thyroid dysfunction; kelp supplements deliver erratic, sometimes excessive amounts. Stay near requEvidence grade B
- Thiamine (B1)Small stores, fast turnover — deficiency (beriberi, Wernicke's) is a medical emergency; routine supplementation rarely does more.Evidence grade B
- Thiamine (B1) for Deficiency syndromesEvidence grade A — Beriberi, Wernicke'sEvidence grade A
- Thiamine (B1) for Diabetic neuropathy (benfotiamine)Evidence grade B — Modest symptom reliefEvidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.