Safety · Supplement
HMB: side effects, safety & interactions
Well tolerated.
- Overall grade
- Grade C
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Well tolerated.
Interactions to respect
No major interactions are on record for HMB at typical doses, but tell your clinician about everything you take.
What HMB is
HMB is a metabolite of the amino acid leucine marketed for muscle preservation and growth.
The honest bottom line
Useful for the untrained, the elderly, and muscle-preservation during illness or dieting; skip it if you're a trained lifter hitting your protein.
Related reading
Entries that share this one's tags or conditions.
- HMBA leucine metabolite that mainly helps the untrained and the catabolic — largely redundant for seasoned lifters eating enough protein.Evidence grade C
- L-Carnitine: side effects, safety & interactionsGenerally safe; high doses can cause a fishy body odor and GI upset. The TMAO/cardiovascular question is unresolved.Evidence grade C
- L-Glutamine: side effects, safety & interactionsVery safe at supplemental doses.Evidence grade C
- L-Ornithine: side effects, safety & interactionsWell tolerated; GI upset at high doses.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.