Safety · Supplement
Gynostemma (Jiaogulan): side effects, safety & interactions
Generally safe; possible additive glucose lowering.
- Overall grade
- Grade C
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
Generally safe; possible additive glucose lowering.
Interactions to respect
Metformin — Additive glucose lowering.
What Gynostemma (Jiaogulan) is
Gynostemma pentaphyllum (jiaogulan) is an adaptogenic herb containing ginseng-like gypenosides.
The honest bottom line
An AMPK-activating adaptogen with early metabolic promise. Low-risk; evidence still thin.
Related reading
Entries that share this one's tags or conditions.
- Berberine: side effects, safety & interactionsGI upset is common. Treat it as a drug: additive hypoglycemia with diabetes medication, CYP-mediated interactions, and aEvidence grade B
- Cinnamon: side effects, safety & interactionsHigh-dose cassia coumarin can stress the liver; additive glucose lowering with diabetes drugs.Evidence grade C
- Green Tea Extract (EGCG): side effects, safety & interactionsBrewed tea is safe. Concentrated extracts carry a rare hepatotoxicity risk; avoid high fasted doses.Evidence grade C
- Akkermansia muciniphila: side effects, safety & interactionsWell tolerated in the trial; long-term safety of a novel single-strain probiotic is not established.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.