Safety · Supplement
CLA (Conjugated Linoleic Acid): side effects, safety & interactions
High-dose synthetic CLA may adversely affect metabolic markers.
- Overall grade
- Grade D
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
Safety profile
High-dose synthetic CLA may adversely affect metabolic markers.
Interactions to respect
No major interactions are on record for CLA (Conjugated Linoleic Acid) at typical doses, but tell your clinician about everything you take.
What CLA (Conjugated Linoleic Acid) is
CLA is a family of linoleic-acid isomers found naturally in dairy and beef and sold synthetically for fat loss.
The honest bottom line
Skip it. The fat-loss effect is negligible in humans and the synthetic isomers may do metabolic harm.
Related reading
Entries that share this one's tags or conditions.
- Chromium: side effects, safety & interactionsGenerally safe at supplemental doses; the issue is lack of benefit, not harm.Evidence grade D
- Cinnamon: side effects, safety & interactionsHigh-dose cassia coumarin can stress the liver; additive glucose lowering with diabetes drugs.Evidence grade C
- CLA (Conjugated Linoleic Acid) for Fat lossEvidence grade D — Not meaningfulEvidence grade D
- Forskolin: side effects, safety & interactionsGenerally tolerated; may lower blood pressure and interact with anticoagulants.Evidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.