Safety · Supplement

Alpha-Lipoic Acid: side effects, safety & interactions

Generally safe; can lower glucose (watch for lows with diabetes meds) and rarely triggers an insulin-autoimmune reaction

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Watch with Berberine: Stacking glucose-lowering agents multiplies monitoring needs.

Generally safe; can lower glucose (watch for lows with diabetes meds) and rarely triggers an insulin-autoimmune reaction.

Metformin — Additive glucose lowering — watch for lows. · Berberine — Stacking glucose-lowering agents multiplies monitoring needs.

Alpha-lipoic acid is a mitochondrial antioxidant that is both fat- and water-soluble, studied mainly in diabetes.

A legitimate option for diabetic neuropathy symptoms and mild glucose improvement. 300–600 mg/day; coordinate with any diabetes medication.

Entries that share this one's tags or conditions.

Cinnamon: side effects, safety & interactionsHigh-dose cassia coumarin can stress the liver; additive glucose lowering with diabetes drugs.Evidence grade C
Green Tea Extract (EGCG): side effects, safety & interactionsBrewed tea is safe. Concentrated extracts carry a rare hepatotoxicity risk; avoid high fasted doses.Evidence grade C
Alpha-Lipoic AcidAn antioxidant with genuine evidence for diabetic neuropathy symptoms and modest insulin-sensitivity effects.Evidence grade B
Alpha-Lipoic Acid for Diabetic neuropathyEvidence grade B — Symptom reliefEvidence grade B

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.