Compound or practice · Supplement
Phosphatidylcholine / Lecithin
A membrane phospholipid and choline source — real for liver and as a choline supply, oversold for memory.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade C · 1 at grade D — 2 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Choline status / liverEvidence grade C
Modest
Smallmixed
- Memory (healthy)Evidence grade D
Weak
Triviallow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Choline status / liver (grade C); Memory (healthy) (grade D).
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
Citicoline (CDP-Choline)Works together
Both raise choline availability.
The evidence in words
What it is
Phosphatidylcholine (the main component of lecithin) is a membrane phospholipid and dietary choline source.
How it works
It supplies choline for acetylcholine and membrane synthesis and supports liver fat handling.
What the evidence shows
Reasonable evidence as a choline source and some support in fatty liver and specific conditions; general memory-enhancement claims in healthy people are weak. A dietary choline supply more than a nootropic.
Safety & interactions
Generally safe; high doses can cause GI upset and body odor. Contributes to TMAO like other choline sources. Citicoline (CDP-Choline) — Both raise choline availability.
Bottom line
A legitimate choline and liver-support source; not a memory booster for healthy people. Sunflower lecithin is a common soy-free form.
Goes with
- Citicoline (CDP-Choline)Both raise choline availability.Evidence grade C
Related reading
Entries that share this one's tags or conditions.
- Phosphatidylcholine / Lecithin for Choline status / liverEvidence grade C — ModestEvidence grade C
- Phosphatidylcholine / Lecithin for Memory (healthy)Evidence grade D — WeakEvidence grade D
- Phosphatidylcholine / Lecithin: side effects, safety & interactionsGenerally safe; high doses can cause GI upset and body odor. Contributes to TMAO like other choline sources.Evidence grade C
- UridineA nucleotide with a plausible membrane-and-dopamine story and thin standalone human data.Evidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.