Compound or practice · Supplement
Passionflower
A gentle GABAergic herb with modest anxiety and sleep signals — a mild, benign calmer.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
3 at grade C — 3 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- AnxietyEvidence grade C
Small trials
Smallmixed
- Sleep qualityEvidence grade C
Modest
Smallmixed
Conditions
How the entry reads its effect on diagnosed conditions: the direction first, then the grade. Never a substitute for the person who treats you.
- Anxiety May improveEvidence grade CMildGrade C
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Anxiety (grade C); Sleep quality (grade C).
- Caution with Benzodiazepines: Additive sedation.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
BenzodiazepinesCaution
Additive sedation.
ValerianWorks together
Common calming-herb combination.
The evidence in words
What it is
Passionflower (Passiflora incarnata) is a traditional calming herb for anxiety and sleep.
How it works
It appears to increase GABA activity, producing mild anxiolysis and sedation.
What the evidence shows
Small trials suggest reduced anxiety (including pre-surgical) and improved sleep quality; effects are modest and studies small. A gentle, low-risk option, often combined with other calming herbs.
How to use it
Standardized extract or tea in the evening or before stressful events.
Safety & interactions
Generally safe; additive sedation with other depressants; avoid in pregnancy. benzodiazepines — Additive sedation. Valerian — Common calming-herb combination.
Bottom line
A mild, benign calming herb for anxiety and sleep. Modest but low-risk; don't stack with sedatives.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- Standardized extract or tea, evening.
Goes with
- ValerianCommon calming-herb combination.Evidence grade C
Related reading
Entries that share this one's tags or conditions.
- Passionflower for AnxietyEvidence grade C — Small trialsEvidence grade C
- ApigeninThe chamomile flavone behind the bedtime-tea calm — mild, benign, thinly studied as an isolated supplement.Evidence grade C
- Lemon BalmA pleasant mint-family herb with small acute anxiety, mood, and sleep signals.Evidence grade C
- Passionflower for Sleep qualityEvidence grade C — ModestEvidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.