Interaction · Supplement
CBD (Cannabidiol) + Statins: use with caution
CBD inhibits CYP3A4 and can raise levels of many drugs, including some statins.
- Overall grade
- Grade B
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Watch with CBD (Cannabidiol): About CBD (Cannabidiol)
The evidence in words
The interaction
CBD (Cannabidiol) and Statins — a caution interaction. CBD inhibits CYP3A4 and can raise levels of many drugs, including some statins.
What to do
Do not combine these casually. The interaction can matter clinically — bring it to the prescriber who manages the medication before stacking them.
About CBD (Cannabidiol)
Cannabidiol is a non-psychoactive compound from cannabis/hemp; a purified prescription form (Epidiolex) treats rare epilepsies.
The bigger picture
Supplement–drug and supplement–supplement interactions are the reason a stack should be read as a system, not a list. This platform's interactions graph maps them; the medication side always belongs with the person who prescribes it.
Related reading
Entries that share this one's tags or conditions.
- Bergamot (Citrus Bergamia) + Statins: use with cautionOverlapping lipid mechanisms — coordinate.Evidence grade B
- CBD (Cannabidiol) + Sedative: use with cautionAdditive sedation with other calming agents.Evidence grade B
- Grapefruit + Statins: use with cautionGrapefruit inhibits CYP3A4, raising levels of simvastatin/atorvastatin and the risk of muscle toxicity.Evidence grade B
- St. John's Wort + Statins: use with cautionInduction can lower levels of CYP3A4-metabolized statins, blunting their effect.Evidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.