Interaction · Supplement
Vitamin D + Calcium: work well together
D improves calcium absorption; the bone benefit needs both.
- Overall grade
- Grade C
- Last revised
- 0
- graded outcomes
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
The evidence in words
The interaction
Vitamin D and Calcium — a synergy interaction. D improves calcium absorption; the bone benefit needs both.
What to do
These two complement each other — taking them together is reasonable and, for the stated reason, may work better than either alone.
About Vitamin D
Vitamin D is a fat-soluble secosteroid the skin makes from UVB sunlight and the gut absorbs from food or supplements. It is measured in blood as 25-hydroxyvitamin D (25(OH)D). Despite the name it behaves like a hormone: the active form, calcitriol, binds a nuclear receptor expressed in most tissues. Deficiency is common at higher latitudes, in darker skin, in the elderly, and in anyone who avoids the sun.
The bigger picture
Supplement–drug and supplement–supplement interactions are the reason a stack should be read as a system, not a list. This platform's interactions graph maps them; the medication side always belongs with the person who prescribes it.
Goes with
Related reading
Entries that share this one's tags or conditions.
- Calcium + Vitamin K2: work well togetherK2 directs calcium to bone, not arteries.Evidence grade C
- Vitamin D + Boron: work well togetherBoron modestly slows vitamin D catabolism.Evidence grade C
- Vitamin D + Magnesium: work well togetherMagnesium is a required cofactor for activating vitamin D; low magnesium blunts the response.Evidence grade C
- Vitamin D + Vitamin K2: work well togetherK2 directs the calcium D mobilizes into bone rather than soft tissue.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.