Vitamin K1 for Warfarin reversal (clinical)

Evidence grade A — Medical use

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade A — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Warfarin reversal (clinical)Medical use	Evidence grade A	Large	high

For warfarin reversal (clinical), Vitamin K1 earns evidence grade A (large effect, high consistency) — there is real evidence here. Medical use

K1 activates clotting factors in the liver via carboxylation; it is the direct antagonist of warfarin, which blocks that recycling.

Obtained from leafy greens; supplementation is rarely needed outside clinical settings. On warfarin, keep intake steady rather than avoiding greens.

Very safe; the key issue is consistency for anyone on vitamin-K-antagonist anticoagulants.

You get enough from greens. If you take warfarin, the rule is steady, consistent vitamin K — not avoidance.

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Entries that share this one's tags or conditions.

Vitamin K1 for Blood clottingEvidence grade A — DefinitionalEvidence grade A
Krill Oil for Omega-3 indexEvidence grade B — Raises index; dose to EPA+DHAEvidence grade B
Vitamin K1: dosage and how to take itLeafy greens; keep intake steady on warfarin.Evidence grade B
Vitamin K1: side effects, safety & interactionsVery safe; the key issue is consistency for anyone on vitamin-K-antagonist anticoagulants.Evidence grade B

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.