Evidence brief · Supplement
Pycnogenol (Pine Bark) for Venous insufficiency
Evidence grade C — Symptom relief
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Venous insufficiencyEvidence grade C
Symptom relief
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Venous insufficiency (grade C).
The evidence in words
The verdict
For venous insufficiency, Pycnogenol (Pine Bark) earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Symptom relief
How it might work
Antioxidant and nitric-oxide-supporting actions improving microcirculation and endothelial function.
How to use it
100–200 mg/day standardized.
Safety & cautions
Generally safe; mild antiplatelet action; additive blood-pressure lowering.
Bottom line
Broad but largely single-source evidence for circulation and skin. Plausible and low-risk; weigh the industry-funding caveat.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 100–200 mg/day standardized.
Goes with
- Pycnogenol (Pine Bark)Read the full Pycnogenol (Pine Bark) monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- Pycnogenol (Pine Bark) for Blood pressureEvidence grade C — ModestEvidence grade C
- Grape Seed Extract for Blood pressureEvidence grade C — ModestEvidence grade C
- Pycnogenol (Pine Bark) for Skin elasticity/UVEvidence grade C — Small trialsEvidence grade C
- Grape Seed Extract for HypertensionEvidence grade C — ModestEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.