Evidence brief · Supplement
HMB for Muscle (trained, adequate protein)
Evidence grade D — Little added benefit
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Muscle (trained, adequate protein)Evidence grade D
Little added benefit
Trivialmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Muscle (trained, adequate protein) (grade D).
The evidence in words
The verdict
For muscle (trained, adequate protein), HMB earns evidence grade D (trivial effect, mixed consistency) — the evidence does not support the claim. Little added benefit
How it might work
It appears to reduce muscle-protein breakdown, which matters most when breakdown is high — detraining, illness, caloric deficit, or the untrained state.
How to use it
3 g/day, split; the free-acid form is absorbed faster.
Safety & cautions
Well tolerated.
Bottom line
Useful for the untrained, the elderly, and muscle-preservation during illness or dieting; skip it if you're a trained lifter hitting your protein.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 3 g/day, split.
Goes with
- HMBRead the full HMB monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- HMB for Muscle (untrained / catabolic)Evidence grade C — Context-dependentEvidence grade C
- HMB: dosage and how to take it3 g/day, split.Evidence grade C
- HMB: side effects, safety & interactionsWell tolerated.Evidence grade C
- L-Carnitine for Diabetic neuropathy (ALCAR)Evidence grade C — Symptom reliefEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.