Evidence brief · Supplement
GABA (Supplement) for Relaxation / stress
Evidence grade D — Poor brain entry
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Relaxation / stressEvidence grade D
Poor brain entry
Triviallow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Relaxation / stress (grade D).
The evidence in words
The verdict
For relaxation / stress, GABA (Supplement) earns evidence grade D (trivial effect, low consistency) — the evidence does not support the claim. Poor brain entry
How it might work
GABA is the main inhibitory neurotransmitter, but supplemental GABA's central effects are limited by poor brain entry; any effect may be via the enteric nervous system.
How to use it
100–300 mg if trialing, evening.
Safety & cautions
Generally safe; additive with other sedatives.
Bottom line
The mechanism argues against it and the evidence is thin. Theanine or glycine are better-supported calm/sleep options.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- If trialing
- 100–300 mg, evening.
Goes with
- GABA (Supplement)Read the full GABA (Supplement) monographEvidence grade D
Related reading
Entries that share this one's tags or conditions.
- L-Theanine for Acute stress / anxietyEvidence grade B — Non-sedating calmEvidence grade B
- L-Theanine for Attention (with caffeine)Evidence grade B — Smoother focus, less jitterEvidence grade B
- L-Theanine for Sleep qualityEvidence grade C — Relaxation, not sedationEvidence grade C
- ApigeninThe chamomile flavone behind the bedtime-tea calm — mild, benign, thinly studied as an isolated supplement.Evidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.